2-AMINO-2-METHYL-1-PROPANOL

MSDS Number: A4572 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: 1-Propanol, 2-amino-2-methyl-; AMP; 2-amino-2-methyl-1-propanol, 99%
CAS No.: 124-68-5
Molecular Weight: 89.14
Chemical Formula: CH3CCH3NH2CH2OH
Product Codes: J.T. Baker: A896 Mallinckrodt: 1990


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  1-Propanol, 2-amino-2-methyl-             124-68-5       99 - 100%    Yes                                                                  
 


3. Hazards Identification

Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES SEVERE EYE IRRITATION AND SKIN IRRITATION. MAY CAUSE EYE BURNS. CAUSES RESPIRATORY TRACT IRRITATION. COMBUSTIBLE LIQUID AND VAPOR.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Information on the human health effects from exposure to this substance is limited.

Inhalation:
Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath.

Ingestion:
No information found, but material is expected to cause irritation or burns to the gastrointestinal tract.

Skin Contact:
Causes severe irritation with redness, pain, and possibly skin burns.

Eye Contact:
Causes severe irritation. May cause redness, pain, blurred vision, and eye damage.

Chronic Exposure:
No information found.

Aggravation of Pre-existing Conditions:
No information found.


4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.

Skin Contact:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Call a physician.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures

Fire:
Flash point: 67C (153F) CC Combustible Liquid and Vapor!

Explosion:
Above the flash point, explosive vapor-air mixtures may be formed. Vapors can flow along surfaces to distant ignition source and flash back.

Fire Extinguishing Media:
Dry chemical, alcohol foam or carbon dioxide. Water spray may be used to keep fire exposed containers cool.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer!


7. Handling and Storage

Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product. Protect against physical damage. Outside or detached storage is preferred. Inside storage should be in a standard flammable liquids storage room or cabinet. Separate from oxidizing materials. Storage and use areas should be No Smoking areas.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.

Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.

Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
Colorless crystalline mass; or viscous liquid, if over the melting point.

Odor:
No information found.

Solubility:
Miscible in water.

Specific Gravity:
0.934

pH:
11.3 For 0.1 molar solution.

% Volatiles by volume @ 21C (70F):
100

Boiling Point:
165C (329F)

Melting Point:
31C (88F)

Vapor Density (Air=1):
3.0

Vapor Pressure (mm Hg):
No information found.

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Copper, brass, aluminum, and oxidizing agents.

Conditions to Avoid:
Cold, heat, flame, ignition sources.


11. Toxicological Information


Oral rabbit LD50: 2900 mg/kg Skin rabbit LD50: >2000mg/kg (ANGUS Chemical Co).

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  1-Propanol, 2-amino-2-methyl-           No          No            None
  (124-68-5)                          


12. Ecological Information

Environmental Fate:
This material is not expected to significantly bioaccumulate. (ANGUS Chemical Co.)

Environmental Toxicity:
This material is not expected to be toxic to aquatic life. The LC50/96-hour values for fish are over 100 mg/l. The EC50/48-hour values for daphnia are over 100 mg/l. (ANGUS Chemical Co.)


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Not regulated.


15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  1-Propanol, 2-amino-2-methyl- (124-68-5)          Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  1-Propanol, 2-amino-2-methyl- (124-68-5)          Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  1-Propanol, 2-amino-2-methyl- (124-68-5)   No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  1-Propanol, 2-amino-2-methyl-              No         No         No         
  (124-68-5)                              
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: No   Fire: Yes Pressure: No
Reactivity: No          (Pure / Liquid)


Australian Hazchem Code: No information found.
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 2 Flammability: 2 Reactivity: 0

Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES SEVERE EYE IRRITATION AND SKIN IRRITATION. MAY CAUSE EYE BURNS. CAUSES RESPIRATORY TRACT IRRITATION. COMBUSTIBLE LIQUID AND VAPOR.

Label Precautions:
Keep away from heat and flame. Keep container closed. Use with adequate ventilation. Avoid breathing vapor. Wash thoroughly after handling. Avoid contact with eyes, skin and clothing.

Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, give large amounts of water to drink. Never give anything by mouth to an unconscious person. In all cases call a physician immediately.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)