RHODAMINE B
MSDS Number: R5400 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: Ammonium,
(o-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)die
thyl-, chloride; FD and C Red No. 19; Basic Violet 10;
Rhodamine O; Tetraethylrhodamine; CI 45170
CAS No.: 81-88-9
Molecular Weight: 479.02
Chemical Formula: C28H31N2O3Cl
Product Codes: J.T. Baker:
U872
Mallinckrodt:
2753
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Rhodamine B 81-88-9 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
CAUTION! MAY BE HARMFUL IF SWALLOWED. MAY CAUSE IRRITATION TO SKIN,
EYES, AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Cancer Causing)
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Code: Blue (Health)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Information on the human health effects from exposure to this substance is
limited.
Inhalation:
May cause irritation to the respiratory tract. Symptoms may include
coughing, sore throat, labored breathing, and chest pain.
Ingestion:
No information found, but compound should be handled as a potential health
hazard. May cause irritation to the gastro-intestinal tract.
Skin Contact:
May cause irritation with redness and pain.
Eye Contact:
May cause irritation, redness and pain.
Chronic Exposure:
Possible cancer hazard based on animal data. Rhodamine dyes can cause
phototoxic or photoallergic reactions.
Aggravation of Pre-existing Conditions:
No information found.
4. First Aid Measures
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an
unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Call a
physician if irritation develops.
Eye Contact:
In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes, lifting upper and lower eyelids occasionally. Call a
physician if irritation persists.
5. Fire Fighting Measures
Fire:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal protective
equipment as specified in Section 8. Spills: Pick up and place in a
suitable container for reclamation or disposal, using a method that does
not generate dust.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
Protect against physical damage. Isolate from incompatible substances.
Containers of this material may be hazardous when empty since they retain
product residues (dust, solids); observe all warnings and precautions
listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures as low as possible. Local exhaust ventilation is generally
preferred because it can control the emissions of the contaminant at its
source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a
half-face dust/mist respirator may be worn. For emergencies or instances
where the exposure levels are not known, use a full-face positive-pressure,
air-supplied respirator. WARNING: Air-purifying respirators do not
protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or
splashing of solutions is possible. Maintain eye wash fountain and
quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Green crystals or reddish-violet powder
Odor:
No information found.
Solubility:
Very soluble in water.
Specific Gravity:
No information found.
pH:
No information found.
% Volatiles by volume @ 21C (70F):
No information found.
Boiling Point:
No information found.
Melting Point:
No information found.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Burning may produce ammonia, carbon monoxide, carbon dioxide, nitrogen
oxides. May produce hydrogen chloride.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers.
Conditions to Avoid:
Incompatibles.
11. Toxicological Information
Toxicological Data:
Oral mouse LD50: 887 mg/kg; investigated as a mutagen, tumorigen,
reproductive effector
Carcinogenicity:
There is limited evidence that this material causes cancer in laboratory
animals. There is no evidence that this material causes cancer in humans.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Rhodamine B (81-88-9) No No 3
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an
appropriate and approved waste disposal facility. Processing, use or
contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Rhodamine B (81-88-9) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Rhodamine B (81-88-9) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Rhodamine B (81-88-9) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Rhodamine B (81-88-9) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Prop 65:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE CANCER.
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 1 Flammability: 0 Reactivity: 0
Label Hazard Warning:
CAUTION! MAY BE HARMFUL IF SWALLOWED. MAY CAUSE IRRITATION TO SKIN, EYES, AND
RESPIRATORY TRACT.
Label Precautions:
Avoid breathing dust.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
If swallowed, give large amounts of water to drink. Never give anything by
mouth to an unconscious person. Call a physician. In case of contact,
immediately flush skin or eyes with plenty of water for at least 15 minutes.
Call a physician if irritation develops or persists. If inhaled, remove to
fresh air. Get medical attention for any breathing difficulty.
Product Use:
Laboratory Reagent.
Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling
of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
************************************************************************************************
Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)