SODIUM SALICYLATE

MSDS Number: S4938 --- Effective Date: 12/08/96


1. Product Identification

Synonyms: Salicylic acid, sodium salt; Sodium o-hydroxybenzoate; Diuretin
CAS No.: 54-21-7
Molecular Weight: 160.09
Chemical Formula: NaC7H5O3
Product Codes: J.T. Baker: 3872 Mallinckrodt: 2094


2. Composition/Information on Ingredients


  Ingredient                                CAS No         Percent   Hazardous                                       
  ---------------------------------------   ------------   -------   ---------        
 
  Sodium Salicylate                         54-21-7        99 - 100%    Yes                                                                  
 


3. Hazards Identification

Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED. AFFECTS CENTRAL NERVOUS SYSTEM. MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.


J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES
Storage Color Code: Orange (General Storage)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
May cause irritation to the respiratory tract. Symptoms may include coughing, sore throat, labored breathing, and chest pain.

Ingestion:
Ingestion of sizable amounts can cause "salicylism", as evidenced by abdominal pain, vomiting, increased respiration, and mental disturbances. Fatalities resulting from respiratory or cardiovascular failure are known. Mean lethal adult dose of salicylates is between 20 and 30 grams.

Skin Contact:
May cause irritation with redness and pain.

Eye Contact:
May cause irritation, redness and pain.

Chronic Exposure:
No information found.

Aggravation of Pre-existing Conditions:
No information found.


4. First Aid Measures

Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.

Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.

Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.

Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention if irritation persists.

Note to Physician:
Gastric lavage with 3 - 5% sodium bicarb to decrease absorption of salicylate ion.


5. Fire Fighting Measures

Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.

Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.

Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.

Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal. Small amounts of residue may be flushed to sewer with plenty of water.


7. Handling and Storage

Keep in a tightly closed container. Protect from physical damage. Store in a cool, dry, ventilated area away from sources of heat, moisture and incompatibilities. Store in the dark. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.

Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.

Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.

Skin Protection:
Wear protective gloves and clean body-covering clothing.

Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance:
Colorless to white crystals; turns pink on exposure to light.

Odor:
Characteristic odor.

Solubility:
111 g/100 g water @ 15C (59F)

Specific Gravity:
No information found.

pH:
5 - 6

% Volatiles by volume @ 21C (70F):
0

Boiling Point:
No information found.

Melting Point:
No information found.

Vapor Density (Air=1):
No information found.

Vapor Pressure (mm Hg):
No information found.

Evaporation Rate (BuAc=1):
No information found.


10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products:
May produce oxides of carbon and the contained metal.

Hazardous Polymerization:
Will not occur.

Incompatibilities:
Ferric salts, lime water, iodine, strong oxidizing agents, silver nitrate, spirit nitrous ether, mineral acids, lead acetate, sodium phosphate powder.

Conditions to Avoid:
Light and incompatibles.


11. Toxicological Information


Oral rat LD50: 930 mg/kg. Investigated as a mutagen, reproductive effector.

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Sodium Salicylate (54-21-7)             No          No            None


12. Ecological Information

Environmental Fate:
No information found.

Environmental Toxicity:
No information found.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Not regulated.


15. Regulatory Information


  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Sodium Salicylate (54-21-7)                       Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Sodium Salicylate (54-21-7)                       Yes   Yes   No     Yes                             
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Sodium Salicylate (54-21-7)                No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Sodium Salicylate (54-21-7)                No         No         No                   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: No   Fire: No  Pressure: No
Reactivity: No          (Pure / Solid) 


Australian Hazchem Code: No information found.
Poison Schedule: No information found.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.


16. Other Information

NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0

Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED. AFFECTS CENTRAL NERVOUS SYSTEM. MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.

Label Precautions:
Avoid contact with eyes, skin and clothing. Wash thoroughly after handling. Avoid breathing dust. Keep container closed. Use with adequate ventilation.

Label First Aid:
If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Get medical attention if irritation develops or persists.

Product Use:
Laboratory Reagent.

Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.

Disclaimer:
************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************ Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)